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TFPI Monoclonal Antibody (OTI4H9), TrueMAB™, OriGene
SDP

Catalog No. 501680949
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100 μL
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50-168-0949 100 μL
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Catalog No. 50-168-0949 Supplier OriGene Supplier No. TA806052
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Mouse Monoclonal Antibody

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predomitly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.

Specifications

Antigen TFPI
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI4H9
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene TFPI
Gene Accession No. P10646
Gene Alias EPI, LACI, TFI, TFPI1
Gene Symbols TFPI
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 29-304 of human TFPI produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7035
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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