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TG Monoclonal Antibody (OTI3E12), TrueMAB™, OriGene
SDP

Catalog No. 501678842
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100 μL
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Catalog No. Quantity
50-167-8842 100 μL
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Catalog No. 50-167-8842 Supplier OriGene Supplier No. TA801456
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Description

Mouse Monoclonal Antibody

Thyroglobulin(Tg) is a glycoprotein homodimer produced predomitly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine.Thyroglobulinis secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

Specifications

Antigen TG
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3E12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene TG
Gene Accession No. P01266
Gene Alias AITD3, TGN
Gene Symbols TG
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 2511-2768 of human TG produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7038
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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