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TGF-alpha Antibody (MF9), Biotin, Novus Biologicals™
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Catalog No. NBP234683B Shop All R&D Systems Products
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NBP234683B 0.1 mL
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Catalog No. NBP234683B Supplier Novus Biologicals Supplier No. NBP234683B
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Description

Mouse Monoclonal Antibody

TGF-alpha Monoclonal specifically detects TGF-alpha in Human, Mouse, Rat, Bovine samples. It is validated for Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen TGF-alpha
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone MF9
Conjugate Biotin
Dilution Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias protransforming growth factor alpha, TFGA, transforming growth factor, alpha, transforming growth factor-alpha
Gene Symbols TGFA
Host Species Mouse
Immunogen A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGF-alpha (exact sequence is proprietary) (Uniprot: P01135)
Molecular Weight of Antigen 6 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Angiogenesis, Cell Cycle and Replication, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 7039
Test Specificity This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Target Species Human, Mouse, Rat, Bovine
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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