TGF alpha Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA585544
Keep as concentrated solution. Positive Control: TGFA-transfected 293T. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Transforming growth factor (TGF) alpha is a 50-aa single-chain polypeptide derived from cleavage of transmembrane pro-TGF alpha. Sharing 42% identity with epidermal growth factor (EGF), TGF alpha binds the EGF receptor and activates downstream signaling pathways. TGF alpha is expressed by activated macrophages, keratinocytes, epithelial cells, and a variety of tumor-derived and transformed cell lines. This growth factor mediates cell proliferation and migration, as well as cellular transformation. Overexpression of TGF alpha has been linked to a variety of cancers, including the breast, colon, and stomach.
|TGFA Antibody; transforming growth factor; alpha Antibody; TFGA Antibody|
|Antigen Affinity Chromatography|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 20% glycerol and 0.025% ProClin 300; pH 7|
|Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TGF alpha.|
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