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TGF-beta Antibody (1D11.16.8), Alexa Fluor™ 532, Novus Biologicals™
SDP

Catalog No. NB001407 Shop All R&D Systems Products
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NB001407 0.1 mL
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Catalog No. NB001407 Supplier Novus Biologicals Supplier No. NBP245137AF532
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Description

Mouse Monoclonal Antibody

TGF-beta Monoclonal specifically detects TGF-beta in Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey samples. It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Sandwich ELISA.

Specifications

Antigen TGF-beta
Applications Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), ELISA
Classification Monoclonal
Clone 1D11.16.8
Conjugate Alexa Fluor 532
Dilution Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Sandwich ELISA
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias CED, DPD1, LAP, TGFB, TGFB1, TGFbeta, transforming growth factor beta 1
Gene Symbols TGFB1
Host Species Mouse
Immunogen Bovine bone-derived TGF-beta 1 and TGF-beta 2
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cytokine Research, Extracellular Matrix
Primary or Secondary Primary
Gene ID (Entrez) 7040
Test Specificity This MAb recognizes TGF beta 1, 2 and 3. Three TGF betas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFbeta's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.
Target Species Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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