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Thyroglobulin Mouse, Clone: SPM517, Novus Biologicals™
SDP

Catalog No. NBP232997B Shop All R&D Systems Products
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0.1 mg
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Catalog No. Quantity
NBP232997B 0.2 mg
NBP232997F 0.02 mg
NBP232997A 0.1 mg
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Catalog No. NBP232997B Supplier Novus Biologicals Supplier No. NBP2329970.2MG

Description

Mouse Monoclonal Antibody

Thyroglobulin Monoclonal antibody specifically detects Antigen in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Immunohistochemistry (Paraffin), Western Blotting.

Specifications

Antigen Thyroglobulin
Applications Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPM517
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry-Paraffin 0.5-1.0ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P01266
Gene Alias AITD3TGN, TDH3, Tg, thyroglobulin
Gene Symbols TG
Host Species Mouse
Immunogen Human thyroid follicular cells
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Cancer, Cell Biology
Primary or Secondary Primary
Gene ID (Entrez) 7038
Test Specificity Thyroglobulin is a 660kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable ma
Target Species Human, Mouse, Rat
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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