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TIMP-2 Antibody (3A4), Alexa Fluor™ 532, Novus Biologicals™
SDP

Catalog No. NP24A32 Shop All R&D Systems Products
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NP24A32 0.1 mL
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Catalog No. NP24A32 Supplier Novus Biologicals Supplier No. NBP254555AF532
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Description

Mouse Monoclonal Antibody

TIMP-2 Monoclonal specifically detects TIMP-2 in Human, Mouse, Rat, Bovine, Guinea Pig, Rabbit, Zebrafish samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen TIMP-2
Applications Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 3A4
Conjugate Alexa Fluor 532
Dilution Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CSC-21Ktissue inhibitor of metalloproteinase 2, metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, Tissue inhibitor of metalloproteinases 2
Gene Symbols TIMP2
Host Species Mouse
Immunogen A synthetic peptide from the N-terminus of human TIMP-2 protein (aa56-66) (DSGNDIYGNPI) (Uniprot: P16035)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 7077
Test Specificity It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Target Species Human, Mouse, Rat, Bovine, Guinea Pig, Rabbit, Zebrafish
Content And Storage Store at 4°C in the dark.
Isotype IgG2a κ
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