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TLR4/MD-2 Complex Monoclonal Antibody (MTS510), Super Bright™ 436, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
$476.00
Specifications
| Antigen | TLR4/MD-2 Complex |
|---|---|
| Clone | MTS510 |
| Concentration | 0.2 mg/mL |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
62-992-482
|
Invitrogen™
62992482 |
100 μg |
Each of 1 for $476.00
|
|
|||||
Description
The MTS510 monoclonal antibody reacts with the mouse Toll-like receptor 4 (TLR4)/MD-2 complex. At least ten members of the Toll family have been identified. This family of type I transmembrane proteins is characterized by an extracellular domain with leuc
MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.Specifications
| TLR4/MD-2 Complex | |
| 0.2 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| Q9JHF9, Q9QUK6 | |
| Ly96, Tlr4 | |
| Primary | |
| Antibody |
| MTS510 | |
| Flow Cytometry | |
| Super Bright 436 | |
| Rat | |
| Mouse | |
| 17087, 21898 | |
| IgG2a κ | |
| 4°C, store in dark, DO NOT FREEZE! | |
| Ly96 |
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