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TOP1MT Antibody (TOP1MT/488), Alexa Fluor™ 750, Novus Biologicals™
SDP

Catalog No. NP247793A70 Shop All R&D Systems Products
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NP247793A70 0.1 mL
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Catalog No. NP247793A70 Supplier Novus Biologicals Supplier No. NBP247793AF750
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Description

Mouse Monoclonal Antibody

TOP1MT Monoclonal specifically detects TOP1MT in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen TOP1MT
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone TOP1MT/488
Conjugate Alexa Fluor 750
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias mitochondrial, mitochondrial DNA topoisomerase I, topoisomerase (DNA) I, mitochondrial
Gene Symbols TOP1MT
Host Species Mouse
Immunogen Recombinant full-length human TOP1MT protein (Uniprot: Q969P6 )
Purification Method Protein A or G purified
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 116447.0
Test Specificity DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG2b κ
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