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TOP1MT Antibody (TOP1MT/488) - Azide and BSA Free, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2477930.1MG
Description
TOP1MT Monoclonal specifically detects TOP1MT in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular), Immunofluorescence, CyTOF-ready.Specifications
TOP1MT | |
Monoclonal | |
1.0 mg/mL | |
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready | |
mitochondrial, mitochondrial DNA topoisomerase I, topoisomerase (DNA) I, mitochondrial | |
Mouse | |
70 kDa | |
0.1 mg | |
Primary | |
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity. | |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | |
IgG2b κ |
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF | |
TOP1MT/488 | |
Unconjugated | |
PBS with No Preservative | |
TOP1MT | |
Recombinant full-length human TOP1MT protein | |
Protein A or G purified | |
RUO | |
116447 | |
Human | |
Purified |
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