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TOP1MT Antibody (TOP1MT/488) - Azide and BSA Free, Novus Biologicals™
SDP

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2477930.1MG

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Catalog No. NBP247793A


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Description

Description

TOP1MT Monoclonal specifically detects TOP1MT in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular), Immunofluorescence, CyTOF-ready.
Specifications

Specifications

TOP1MT
Monoclonal
1.0 mg/mL
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
mitochondrial, mitochondrial DNA topoisomerase I, topoisomerase (DNA) I, mitochondrial
Mouse
70 kDa
0.1 mg
Primary
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
IgG2b κ
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
TOP1MT/488
Unconjugated
PBS with No Preservative
TOP1MT
Recombinant full-length human TOP1MT protein
Protein A or G purified
RUO
116447
Human
Purified
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