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TOP1MT Antibody (TOP1MT/488), Novus Biologicals™
SDP

Catalog No. NBP24436002 Shop All R&D Systems Products
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NBP24436002 0.2 mg
NBP24436000 0.02 mg
NBP24436001 0.1 mg
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Catalog No. NBP24436002 Supplier Novus Biologicals Supplier No. NBP2443600.2MG

Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

TOP1MT Monoclonal antibody specifically detects TOP1MT in Human samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, SDS-Page, Flow (Intracellular), Immunofluorescence.

Specifications

Antigen TOP1MT
Applications Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Classification Monoclonal
Clone TOP1MT/488
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. Q969P6
Gene Alias mitochondrial, mitochondrial DNA topoisomerase I, topoisomerase (DNA) I, mitochondrial
Gene Symbols TOP1MT
Host Species Mouse
Immunogen Recombinant full-length human TOP1MT protein
Molecular Weight of Antigen 70 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116447
Test Specificity DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG2b κ
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