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TOPORS Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501561972
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50-156-1972 100 μL
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Catalog No. 50-156-1972 Supplier Bethyl Laboratories, Inc Supplier No. A302179A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.

Specifications

Antigen TOPORS
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene TOPORS
Gene Accession No. Q9NS56
Gene Alias LUN, p53-binding protein 3, P53BP3, retinitis pigmentosa 31 (autosomal domit), RP31, SUMO1-protein E3 ligase Topors, topoisomerase I binding, arginine/serine-rich, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase, Topoisomerase I-binding arginine/serine-rich protein, topoisomerase I-binding RING finger protein, TP53BPL, tumor suppressor p53-binding protein 3
Gene Symbols TOPORS
Host Species Rabbit
Immunogen Between 995 and 1045
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10210
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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