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  6. TOX3 Antibody (TOX3/1123) - Azide and BSA Free, Novus Biologicals™

TOX3 Antibody (TOX3/1123) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NBP247748A Shop All R&D Systems Products
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NBP247748A 0.1 mg
NBP247748B 0.2 mg
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Catalog No. NBP247748A Supplier Novus Biologicals Supplier No. NBP2477480.1MG
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Description

Mouse Monoclonal Antibody

TOX3 Monoclonal specifically detects TOX3 in Chicken, Human samples. It is validated for ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Protein Array, Western Blot.

Specifications

Antigen TOX3
Applications ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Protein Array, Western Blot
Classification Monoclonal
Clone TOX3/1123
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Gene Symbols TOX3
Host Species Mouse
Immunogen Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Molecular Weight of Antigen 63 kDa
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27324
Test Specificity It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Target Species Chicken, Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG2b κ
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