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  6. TP53BP1 Monoclonal Antibody (OTI6D9), TrueMAB™, OriGene 

TP53BP1 Monoclonal Antibody (OTI6D9), TrueMAB™, OriGene
SDP

Catalog No. 501681326
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100 μL
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Catalog No. Quantity
50-168-1326 100 μL
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Catalog No. 50-168-1326 Supplier OriGene Supplier No. TA806950
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Description

Mouse Monoclonal Antibody

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.

Specifications

Antigen TP53BP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI6D9
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene TP53BP1
Gene Accession No. Q12888
Gene Alias 53BP1, TDRD30, TP53, p202, p53BP1
Gene Symbols TP53BP1
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1-300 of human TP53BP1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7158
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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