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Tocris Bioscience™ TPCA-1
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Catalog No. 255910
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10 mg
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Catalog No. Quantity
25-591-0 10 mg
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Catalog No. 25-591-0 Supplier Tocris Bioscience™ Supplier No. 2559/10
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Description

Potent, selective inhibitor of IKKβ

Potent, selective inhibitor of IκB kinase (IKK) β (IC50 = 17.9 nM) that displays > 22-fold selectivity over IKKα and > 550-fold selectivity over other kinases and enzymes. Inhibits production of pro-inflammatory cytokines in vitro and in vivo and inhibits NF-κB nuclear localization. Reduces the severity and onset of collagen-induced arthritis; anti-inflammatory.

Chemical Identifiers

CAS 507475-17-4
Molecular Formula C12H10FN3O2S

Specifications

Quantity 10 mg
Formula Weight 279.29
Purity >97%
Molecular Weight (g/mol) 279.289
Chemical Name or Material TPCA-1

Safety and Handling

Recommended Storage Desiccate at -20°C
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