TPM4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8974	Proteintech Group Inc 137411AP150UL	150 μL

Description

TPM4 (tropomyosin 4) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 plays a central role in association with the troponin complex in the calcium dependent regulations of vertebrate striated muscle contraction. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: TPM4
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P09495, P67936, Q6IRU2
• Gene ID (Entrez): 24852, 326618, 7171
• Immunogen: TPM4 Fusion Protein Ag4679
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: TPM4

• Concentration: 0.13 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: TM30p1, TPM4, tropomyosin 4, Tropomyosin alpha 4 chain
• Gene Symbols: Tpm4
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody