Invitrogen™ Transferrin Receptor Monoclonal Antibody (OX-26)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
MA170033	Invitrogen™ MA170033	250 μg
PIMA517555	Invitrogen™ MA517555	500 μg

Description

Transferrin Receptor Monoclonal Antibody for Western Blot, IHC (F), Flow, IP

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

Specifications

• Antigen: Transferrin Receptor
• Concentration: 1 mg/mL
• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q99376
• Gene ID (Entrez): 64678
• Immunogen: PHA activated lymph node cells of a PVG rat.
• Product Type: Antibody

• Clone: OX-26
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG2a
• Target Species: Rat
• Gene: TFRC
• Gene Alias: 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
• Gene Symbols: TFRC
• Primary or Secondary: Primary
• Purification Method: Protein G