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Invitrogen™ Transferrin Receptor Recombinant Human Monoclonal Antibody (7H12)
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Catalog No. FEMA550098
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100 μL
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FEMA550098 100 μL
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Catalog No. FEMA550098 Supplier Invitrogen™ Supplier No. MA550098
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Description

Human Recombinant Monoclonal Antibody

Transferrin Receptor Recombinant Monoclonal Antibody for ELISA

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Transferrin Receptor
Applications ELISA, Neutralization
Classification Recombinant Monoclonal
Clone 7H12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene TFRC
Gene Accession No. P02786
Gene Alias 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Gene Symbols TFRC
Host Species Human
Immunogen Recombinant Human TFRC protein.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7037
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG1
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