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Invitrogen™ Transferrin Receptor Recombinant Rabbit Monoclonal Antibody (040), PE
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Catalog No. PIMA546713
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100 Tests
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PIMA546713 100 Tests
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Catalog No. PIMA546713 Supplier Invitrogen™ Supplier No. MA546713
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Description

Rabbit Recombinant Monoclonal Antibody

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human Transferrin Receptor (CD71) (Cys89-Phe760) and conjugated with PE under optimum conditions, the unreacted PE was removed. Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Transferrin Receptor
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone 040
Concentration 100 μg/mL
Conjugate PE
Formulation PBS with 0.5% BSA and 0.09% sodium azide
Gene TFRC
Gene Accession No. P02786
Gene Alias 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Gene Symbols TFRC
Host Species Rabbit
Immunogen Recombinant protein ecoding Human Transferrin Receptor (Cys89-Phe760).
Purification Method Protein A
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7037
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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