Invitrogen™ TRAPPC10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA593214

Catalog No. PIPA593214

Description

Immunogen sequence: MDASEEPLPP VIYTMENKPI VTCAGDQNLF TSVYPTLSQQ LPREPMEWRR SYGRAPKMIH LESNFVQFKE ELLPKEGNKA LLTFPFLHIY WTECCDTEVY KATVKDDLTK WQNVLKAHSS VDWLIVIVEN DAKKKNKTNI LPRTSIVDKI RNDFCNKQSD RCVVLSDPLK DSSRTQESWN AFLTKLRTLL LMSFTKNLGK FEDDMRTLRE KRTEPGWSFC EYFMVQEELA FVFEMLQQFE DALVQYDELD ALFSQYVVNF; Positive Samples: Mouse kidney, Rat lung; Cellular Location: Golgi apparatus, cis-Golgi network.

TRAPPC10, also known as TMEM1 (transmembrane protein 1), EHOC1 (epilepsy holoprosencephaly candidate 1 protein) or GT334, is a widely expressed 1,259 amino acid protein that may function in vesicular transport. Despite its name, TRAPPC10 does not contain transmembrane domains. It is the human ortholog of the yeast Trs130 protein and its structure and function appears to be conserved. Localizing to the cis-Golgi apparatus, TRAPPC10 is believed to be involved in transport from the endoplasmic reticulum (ER) to the Golgi functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Mutations in the gene encoding TRAPPC10 may be involved in autoimmune polyglandular disease type 1 or Unverricht-Lundborg disease, an autosomal recessive type of progressive myoclonic epilepsy.

Specifications

• Antigen: TRAPPC10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRAPPC10
• Gene Alias: B230307C21Rik; EHOC1; EHOC-1; epilepsy holoprosencephaly candidate 1 protein; epilepsy holoprosencephaly candidate-1 protein; Gm870; GT334; Protein GT334; TMEM1; trafficking protein particle complex 10; trafficking protein particle complex subunit 10; trafficking protein particle complex subunit 10; LOW QUALITY PROTEIN: trafficking protein particle complex subunit 10; trafficking protein particle complex subunit 130; trafficking protein particle complex subunit TMEM1; transmembrane protein 1; transport protein particle subunit TMEM1; TRAPP 130 kDa subunit; TRAPP subunit TMEM1; trappc10; TRS130; TRS30; wu:fc21a02
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 216131, 309678
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.05 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q3TLI0
• Gene Symbols: TRAPPC10
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TRAPPC10 (NP_0032653).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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