TRF2 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-155-8468	Bethyl Laboratories, Inc A300796AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt.

TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length (1). TRF2, like TRF1 contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes (1). TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini (2). The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells (2). Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types (3).

Specifications

• Antigen: TRF2
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: TRBF2, TRF2
• Gene Symbols: TERF2
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q15554
• Gene ID (Entrez): 7014
• Immunogen: Between 375 and 425
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: TERF2