Trifluoromethanesulfonic anhydride, 98%, Thermo Scientific Chemicals

Description

Alfa Aesar Trifluoromethanesulfonic anhydride, 98%, Quantity: 250g, Boiling Point: 81 deg.C to 83 deg.C, Melting Point: -80 deg.C, Molecular Weight: 282.127, Percent Purity: 98%, Beilstein: 1813600, CAS: 358-23-6, ChEBI: CHEBI:48509, Density: 1.72

Trifluoromethanesulfonic anhydride is used to convert phenols and imine into triflic ester and NTf group. It is a strong electrophile used for the introduction of triflyl group in chemical synthesis. It serves as a reagent in the preparation of alkyl and vinyl triflates, and for the stereoselective synthesis of mannosazide methyl uronate donors. It acts as a catalyst for glycosylation with anomeric hydroxy sugars to prepare polysaccharides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trifluoromethanesulfonic anhydride is used to convert phenols and imine into triflic ester and NTf group. It is a strong electrophile used for the introduction of triflyl group in chemical synthesis. It serves as a reagent in the preparation of alkyl and vinyl triflates, and for the stereoselective synthesis of mannosazide methyl uronate donors. It acts as a catalyst for glycosylation with anomeric hydroxy sugars to prepare polysaccharides.

Solubility
Miscible with dichloromethane. Immiscible with hydrocarbons.

Notes
Moisture sensitive. Incompatible with water, strong bases, strong oxidizing agents, acids and alcohols.

Specifications

• Melting Point: -80°C
• Density: 1.72
• Boiling Point: 81°C to 83°C
• Refractive Index: 1.321
• Linear Formula: (CF₃SO₂)₂O
• Quantity: 10 g
• UN Number: UN3265
• Beilstein: 1813600
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with dichloromethane. Immiscible with hydrocarbons.
• Formula Weight: 282.13
• Percent Purity: 98%
• Chemical Name or Material: Trifluoromethanesulfonic anhydride

Safety and Handling

Hazard Category	H290-H302-H314-H335
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P234-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P390-P501c
DOTInformation	Hazard Class: 8; Packaging Group: I
EINECSNumber	206-616-8
RTECSNumber	PB2772000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only