TRIM29 Antibody (TRIM29/1042), Alexa Fluor™ 750, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP247809AF750

Catalog No. NB007394

Description

TRIM29 Monoclonal specifically detects TRIM29 in Human samples. It is validated for Western Blot.

Specifications

• Antigen: TRIM29
• Classification: Monoclonal
• Conjugate: Alexa Fluor 750
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: TRIM29
• Immunogen: Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein (Uniprot: Q14134)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG2b κ

• Applications: Western Blot, Flow Cytometry, Immunofluorescence
• Clone: TRIM29/1042
• Dilution: Western Blot, Flow Cytometry, Immunofluorescence
• Gene Alias: Ataxia telangiectasia group D-associated protein, ATDC, ATDC ataxia-telangiectasia group D-associated protein, FLJ36085, tripartite motif containing 29, tripartite motif protein TRIM29, tripartite motif-containing 29, tripartite motif-containing protein 29
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Test Specificity: It recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ∽90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
• Content And Storage: Store at 4°C in the dark.