Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Troglitazone, Tocris Bioscience™
GREENER_CHOICE

Catalog No. 311450
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Selective PPARγ agonist; antidiabetic agent

Selective PPARγ receptor agonist (EC50 values are 780 and 555 nM at murine and human PPARγ receptors respectively). Displays no activity at PPARα or PPARδ receptors. Antidiabetic agent; exerts potent glucose-lowering effects in insulin-resistant diabetic mice. Displays anti-invasive effect on human breast cancer cells; reduces migration, adhesion and spreading on fibronectin-coated plates. Also inhibits cell growth of hematopoietic cell lines. Inhibits lamellipodia formation and actin polymerization.

Chemical Identifiers

CAS 97322-87-7
Molecular Formula C24H27NO5S
Molecular Weight (g/mol) 441.542
InChI Key GXPHKUHSUJUWKP-UHFFFAOYSA-N
Synonym troglitazone, rezulin, romglizone, prelay, romozin, noscal, rezulin tn, troglitazona, troglitazonum, ccris 8969
PubChem CID 5591
ChEBI CHEBI:9753
IUPAC Name 5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
SMILES CC1=C(C(=C2CCC(OC2=C1C)(C)COC3=CC=C(C=C3)CC4C(=O)NC(=O)S4)C)O

Specifications

Quantity 50 mg
Formula Weight 441.54
Percent Purity 98%
Chemical Name or Material Troglitazone
Recommended Storage Store at -20°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.