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TROP-2 Antibody (TACSTD2/2152), DyLight 650, Novus Biologicals™
SDP

Catalog No. NB008800 Shop All R&D Systems Products
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NB008800 0.1 mL
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Catalog No. NB008800 Supplier Novus Biologicals Supplier No. NBP275746C
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Description

Mouse Monoclonal Antibody

TROP-2 Monoclonal specifically detects TROP-2 in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen TROP-2
Applications Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone TACSTD2/2152
Conjugate DyLight 650
Dilution Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, TROP2GA7331, tumor-associated calcium signal transducer 2
Gene Symbols TACSTD2
Host Species Mouse
Immunogen Recombinant fragment of human TROP-2 protein (around aa 31-274) (exact sequence is proprietary) (Uniprot: P09758 )
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Signal Transduction
Primary or Secondary Primary
Test Specificity TROP-2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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