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Invitrogen™ TROP2 Polyclonal Antibody
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Catalog No. PIPA547074
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100 μg
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PIPA547074 100 μg
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Catalog No. PIPA547074 Supplier Invitrogen™ Supplier No. PA547074
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Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 30% cross-reactivity with recombinant human TROP-2 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TROP2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene TACSTD2
Gene Accession No. P09758, Q6P9Z6, Q8BGV3
Gene Alias 40kD glycoprotein, identified by monoclonal antibody GA733; C80403; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; EGP1; EGP-1; epithelial glycoprotein-1; GA733; GA7331; GA733-1; gastrointestinal tumor-associated antigen GA7331; GP50; Ly97; lymphocyte antigen 97; M1S1; Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; pancreatic carcinoma marker protein GA7331; pancreatic carcinoma marker protein GA733-1; parturition-related protein 1; Prp1; TACD2; TACSTD2; Trop2; truncated TACSTD2; tumor-associated calcium signal transducer 2; tunor-associated calcium signal transducer 2
Gene Symbols TACSTD2
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse TROP-2 Ser82-Thr268.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4070, 494343, 56753
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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