Invitrogen™ TRPC4AP Polyclonal Antibody

Catalog No.	Quantity
PIPA5106444	100 μL

Catalog No. PIPA5106444

Supplier: Invitrogen™ PA5106444

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TRPC4AP.

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.

Specifications

• Antigen: TRPC4AP
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: TRPC4AP
• Gene Accession No.: Q8TEL6, Q9JLV2
• Gene Alias: 4833429F06Rik; C20orf188; D2Ertd113e; hypothetical protein; mFLJ00177; PPP1R158; protein phosphatase 1, regulatory subunit 158; Protein TAP1; Protein TRUSS; Rabex-5/Rin2-interacting protein; short transient receptor potential channel 4 associated protein; short transient receptor potential channel 4-associated protein; TAP1 protein; TNF-receptor; TNF-receptor ubiquitous scaffolding/signaling protein; TP4AP; transient receptor potential cation channel subfamily C member 4 associated protein; transient receptor potential cation channel, subfamily C, member 4 associated protein; transient receptor protein 4, associated protein; TRP4-associated protein; Trp4-associated protein TAP1; Trpc4ap; trpc4-associated protein; Trrp4ap; TRUSS; tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein
• Gene Symbols: TRPC4AP
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human TRPC4AP(Accession Q8TEL6), corresponding to amino acid residues V6-Q56.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 26133, 362247, 56407
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG