Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. NB247773488

TTF-1/ NKX2-1 Antibody (8G7G3/1 + NX2.1/690), Alexa Fluor™ 488, Novus Biologicals™
SDP

Catalog No. NB247773488 Shop All R&D Systems Products
Change view
Click to view available options
Quantity:
0.1 mL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
NB247773488 0.1 mL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. NB247773488 Supplier Novus Biologicals Supplier No. NBP247773AF488
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

TTF-1 / NKX2-1 Monoclonal specifically detects TTF-1 / NKX2-1 in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen TTF-1 / NKX2-1
Applications Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 8G7G3/1 + NX2.1/690
Conjugate Alexa Fluor 488
Dilution Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias benign chorea, Homeobox protein NK-2 homolog A, homeobox protein Nkx-2.1, NK2 homeobox 1, NK-2 homolog A, NKX2ANKX2.1, Thyroid nuclear factor 1, Thyroid transcription factor 1BHC, TITF1TEBP, TTF1, TTF1BCH, TTF-1NK-2
Gene Symbols NKX2-1
Host Species Mouse
Immunogen Rat full length TTF-1/ NKX2-1 recombinant protein (8G7G3/1); Recombinant TTF-1/ NKX2-1 protein (NX2.1/690) (Uniprot: P43699)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Membrane Trafficking and Chaperones, Tumor Biomarkers
Primary or Secondary Primary
Gene ID (Entrez) 7080
Test Specificity Recognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
Target Species Human, Mouse, Rat
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.