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TYRP1 Antibody (TYRP1/807) - IHC-Prediluted, Novus Biologicals™
SDP

Catalog No. NBP248128 Shop All R&D Systems Products
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NBP248128 7 mL
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Catalog No. NBP248128 Supplier Novus Biologicals Supplier No. NBP248128
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Description

Mouse Monoclonal Antibody

TYRP1 Monoclonal specifically detects TYRP1 in Human, Mouse samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen TYRP1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone TYRP1/807
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 1.14.18.1, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP
Gene Symbols TYRP1
Host Species Mouse
Immunogen Recombinant full-length human TYRP1 protein (Uniprot: P17643)
Molecular Weight of Antigen 75 kDa
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Cancer
Primary or Secondary Primary
Gene ID (Entrez) 7306
Test Specificity It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Target Species Human, Mouse
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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