TYRP1 Mouse anti-Human, Mouse, Clone-TYRP1/807, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP254306100UG

Catalog No. NB254306100

Description

TYRP1 Monoclonal specifically detects TYRP1 in Human, Mouse samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: TYRP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 3 - 6 ug/ml, CyTOF-ready
• Gene Alias: b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 1.14.18.1, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP
• Host Species: Mouse
• Molecular Weight of Antigen: 75 kDa
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
• Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
• Clone: TYRP1/807
• Conjugate: Unconjugated
• Formulation: PBS with No Preservative
• Gene Symbols: TYRP1
• Immunogen: Recombinant full-length human TYRP1 protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 7306
• Target Species: Human, Mouse
• Isotype: IgG2a κ