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TYRP1 Mouse anti-Human, Mouse, Clone-TYRP1/807, Novus Biologicals™

Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP254306200UG
Description
Human chromosome location: 9p23 IHC-P: Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA pH 9.0 for 10-20 min followed by cooling at RT for 20 minutesSpecifications
TYRP1 | |
Monoclonal | |
1 mg/mL | |
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 3 - 6 ug/ml, CyTOF-ready | |
b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 1.14.18.1, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP | |
Mouse | |
75 kDa | |
200 μg | |
Primary | |
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. | |
Store at -20 to -80C. Avoid freeze-thaw cycles. |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF | |
TYRP1/807 | |
Unconjugated | |
PBS with No Preservative | |
TYRP1 | |
Recombinant full-length human TYRP1 protein | |
Protein A or G purified | |
RUO | |
7306 | |
Human, Mouse | |
IgG2a κ |
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