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TYRP1 Mouse, Clone: SPM456, Novus Biologicals™
SDP

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2329070.2MG

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Catalog No. NBP232907B

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.


Description

Description

TYRP1 Monoclonal antibody specifically detects Antigen in Human, Mouse samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry (Frozen).
Specifications

Specifications

TYRP1
Monoclonal
Unconjugated
PBS with 0.05% BSA. with 0.05% Sodium Azide
b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 1.14.18.1, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP
Mouse
75 kDa
0.2 mg
Primary
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Store at 4C.
IgG2a κ
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
SPM456
Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
P17643
TYRP1
SK-MEL-23 cells
Protein A purified
RUO
7306
Human, Mouse
Purified
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