UCH-L1/PGP9.5 Mouse, Clone: SPM575, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2328960.1MG
DescriptionUCH-L1/PGP9.5 Monoclonal antibody specifically detects Antigen in Bovine, Canine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep, Zebrafish samples. It is validated for Immunocytochemistry/Immunofluorescence, Western Blotting.
|Western Blot 0.5-1ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunocytochemistry 1:500|
|EC 18.104.22.168, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1|
|Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission|
|Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish|
|Western Blot, Immunocytochemistry, Immunofluorescence|
|PBS with 0.05% BSA. with 0.05% Sodium Azide|
|Native UchL1 (PGP9.5) protein from brain|
|Protein A purified|
|Store at 4C.|
|This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.|
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