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UCH-L1/PGP9.5 Mouse, Clone: SPM575, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2328960.1MG

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Catalog No. NBP232896A


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Description

Description

UCH-L1/PGP9.5 Monoclonal antibody specifically detects Antigen in Bovine, Canine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep, Zebrafish samples. It is validated for Immunocytochemistry/Immunofluorescence, Western Blotting.
Specifications

Specifications

UCH-L1/PGP9.5
SPM575
Western Blot 0.5-1ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunocytochemistry 1:500
P09936
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
Mouse
IgG2a Kappa
0.1 mg
Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission
Primary
7345
Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish
Western Blot, Immunocytochemistry, Immunofluorescence
Unconjugated
PBS with 0.05% BSA. with 0.05% Sodium Azide
Purified
UCHL1
Native UchL1 (PGP9.5) protein from brain
Protein A purified
RUO
Store at 4C.
Monoclonal
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
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