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UCH-L1/PGP9.5 Mouse, Clone: SPM575, Novus Biologicals™
SDP

Catalog No. NBP232896B Shop All R&D Systems Products
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Catalog No. Quantity
NBP232896B 0.2 mg
NBP232896F 0.02 mg
NBP232896A 0.1 mg
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Catalog No. NBP232896B Supplier Novus Biologicals Supplier No. NBP2328960.2MG

Description

Mouse Monoclonal Antibody

UCH-L1/PGP9.5 Monoclonal antibody specifically detects Antigen in Bovine, Canine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep, Zebrafish samples. It is validated for Immunocytochemistry/Immunofluorescence, Western Blotting.

Specifications

Antigen UCH-L1/PGP9.5
Applications Western Blot, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone SPM575
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunocytochemistry 1:500
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P09936
Gene Alias EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
Gene Symbols UCHL1
Host Species Mouse
Immunogen Native UchL1 (PGP9.5) protein from brain
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission
Primary or Secondary Primary
Gene ID (Entrez) 7345
Test Specificity This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Target Species Human, Mouse, Rat, Pig, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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