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Tocris Bioscience™ UNC 0642

Name: Tocris Bioscience&trade; UNC 0642
Brand: Tocris Bioscience&trade;
SKU: 51-321-0
Price: 387.44 USD

Potent and selective G9a and GLP inhibitor

Supplier: Tocris Bioscience™ 5132/10

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Catalog No. 51-321-0

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Description

UNC 0642 is a potent and selective G9a and GLP histone lysine methyltransferase inhibitor (IC50 < 2.5 nM) that exhibits >2,000-fold selectivity for G9a and GLP over PRC2-EZH2 and >20,000-fold selectivity over other methyltransferases. UNC 0642 reduces H3K9 dimethylation levels in MDA-MB-231 cells (IC50 = 110 nM), and displays modest brain penetration in vivo.

Specifications

Purity	>99%
Quantity	10 mg
Molecular Weight (g/mol)	546.7

Content And Storage	-20°C
Product Type	UNC 0642
Inhibitors	UNC 0642

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Tocris Bioscience™ UNC 0642

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