Thermo Scientific Chemicals uPA Inhibitor II, UK122

Description

A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activatoruPA Inhibitor II, UK122 acts as a potent, selective and active-site targeting urokinase-type plasminogen activator (uPA) inhibitor. However, its activity against trypsin, thrombin, tPA, and plasmin is greatly reduced. It is also effectively inhibits the migration (80% inhibition) and invasion (68% inhibition) of uPA-expressing CFPAC-1 pancreatic cells, without affecting its proliferation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activator

Specifications

• Quantity: 25 mg
• Description: Yellow
• Content And Storage: 2°C to 8°C
• For Use With (Application): A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activator
• Molecular Formula: C₁₇H₁₃N₃O₂·CF₃CO₂H
• Formula Weight: 405.30g/mol
• Sensitivity: Light Sensitive
• Product Type: Signal Transduction Reagent
• Form: Solid

Safety and Handling

SDS

RUO – Research Use Only