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USP20/VDU2 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
$151.31
Specifications
Antigen | USP20/VDU2 |
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Applications | Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Form | Liquid |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-155-9490
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Bethyl Laboratories, Inc
A301189AT |
20 μL |
Each of 1 for $151.31
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Description
The recommended shelf life for this product is 1 year from date of receipt.
Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.Specifications
USP20/VDU2 | |
Polyclonal | |
Liquid | |
RUO | |
TBS with 0.1% BSA and 0.09% sodium azide | |
USP20; VDU2; ubiquitin specific protease 20; KIAA1003; pVHL-interacting deubiquitinating enzyme 2; ubiquitin specific peptidase 20; LSFR3A | |
Between 863 and 913 | |
Primary | |
4° C | |
USP20 |
Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse | |
Q8C6M1, Q9Y2K6 | |
10868, 74270 | |
IgG | |
Antigen affinity chromatography | |
Antibody |
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