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USP20/VDU2 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

$151.31

Specifications

Antigen USP20/VDU2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Form Liquid
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-155-9490
Encompass_Preferred
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Bethyl Laboratories, Inc
A301189AT
20 μL
Each of 1 for $151.31
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Description

Description

The recommended shelf life for this product is 1 year from date of receipt.

Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Specifications

Specifications

USP20/VDU2
Polyclonal
Liquid
RUO
TBS with 0.1% BSA and 0.09% sodium azide
USP20; VDU2; ubiquitin specific protease 20; KIAA1003; pVHL-interacting deubiquitinating enzyme 2; ubiquitin specific peptidase 20; LSFR3A
Between 863 and 913
Primary
4° C
USP20
Western Blot
Unconjugated
Rabbit
Human, Mouse
Q8C6M1, Q9Y2K6
10868, 74270
IgG
Antigen affinity chromatography
Antibody
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