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Invitrogen™ UVRAG Polyclonal Antibody
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Catalog No. PIPA572818
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100 μg
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PIPA572818 100 μg
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Catalog No. PIPA572818 Supplier Invitrogen™ Supplier No. PA572818
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Rabbit Polyclonal Antibody

UVRAG Polyclonal Antibody for Western Blot, IHC (P), ELISA

UVRAG is predicted to contain a coiled-coil structure and is likely to be metabolically unstable based on the occurrence of a strong PEST domain. It interacts with Beclin 1, leading to activation of autophagy and thereof inhibition of tumorigenicity of human colon cancer cells. The gene for UVRAG protein is localized on human chromosome 11q13. 5 and complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells. The gene has been extremely well conserved during evolution, implying an important role for this gene product in cell metabolism. Chromosomal aberrations involving this gene are associated with left-right axis malformation, and mutations in this gene have been associated with colon cancer. The protein is highly expressed in human brain, lung, kidney and liver.
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Specifications

Antigen UVRAG
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Uvrag
Gene Accession No. Q8K245, Q9P2Y5
Gene Alias 9530039D02Rik; AI648770; BB124205; beclin 1 binding protein; DHTX; disrupted in heterotaxy; hypothetical protein; p63; UV radiation resistance associated; UV radiation resistance associated gene; UV radiation resistance-associated gene protein; UV radiation resistance-associated protein; UVRAG; Uvrag1; Uvragl; VPS38
Gene Symbols Uvrag
Host Species Rabbit
Immunogen UVRAG antibody for an 18 amino acid peptide near the carboxy terminus of human UVRAG. The immunogen is within amino acids 490 - 540 of UVRAG.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7405, 78610
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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