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  6. Varenicline tartrate, Tocris Bioscience™ 

Varenicline tartrate, Tocris Bioscience™

Catalog Number p-4816632
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
375815-87-5
C17H19N3O6
361.354
TWYFGYXQSYOKLK-ZBABXEQTSA-N
varenicline tartrate
124080896
C1C2CNCC1C3=CC4=NC=CN=C4C=C23.C(C(C(=O)O)O)(C(=O)O)O
This item is not returnable. View return policy
375815-87-5
C17H19N3O6
361.354
TWYFGYXQSYOKLK-ZBABXEQTSA-N
varenicline tartrate
124080896
C1C2CNCC1C3=CC4=NC=CN=C4C=C23.C(C(C(=O)O)O)(C(=O)O)O

Description

Selective α4β2 partial agonist; orally active

Orally active, subtype-selective partial agonist at α4β2 nicotinic receptors (Ki values are 0.06, 240, 322 and 3540 nM for α4β2, α3β4, α7, α1βγδ receptors respectively). Reduces nicotine-evoked dopamine release in vitro and decreases nicotine self-administration in vivo. Also potently activates PSAM4-5-HT3 and PSAM4-GlyR chimeric ion channels (EC50 values are 4 and 1.6 nM, respectively)
Quantity 10 mg
Formula Weight 361.37
Percent Purity >99%
Chemical Name or Material Varenicline tartrate

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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