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Tocris Bioscience™ Vatalanib succinate
Potent VEGFR inhibitor; also aromatase inhibitor
$131.20 - $548.00
Specifications
| Chemical Name or Material | N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate |
|---|---|
| Molecular Formula | C20H15ClN4.C4H6O4 |
| CAS | 212142-18-2 |
| Product Type | Target: VEGF Receptor Inhibitors |
| Formula Weight | 464.9 |
Description
Potent VEGFR inhibitor (IC50 values are 37 and 77 nM for VEGFR-2 and -1, respectively). Inhibits proliferation, migration and survival of HUVECs in vitro and inhibits growth, vascularization and metastasis of tumors expressing VEGFR in mouse models. Also inhibits PDGFR-β, c-Kit and c-Fms. Potent aromatase inhibitor (IC50 = 50 nM). Orally available.Specifications
| N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate | |
| 212142-18-2 | |
| 464.9 |
| C20H15ClN4.C4H6O4 | |
| Target: VEGF Receptor Inhibitors |
Safety and Handling
Recommended Storage : Store at −20°C
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