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Tocris Bioscience™ Vatalanib succinate

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Quantity:
10 mg
50 mg
Description
Vatalanib succinate is a potent VEGFR inhibitor (IC50 values are 37 and 77 nM for VEGFR-2 and -1, respectively). Inhibits proliferation, migration and survival of HUVECs in vitro and inhibits growth, vascularization and metastasis of tumors expressing VEGFR in mouse models. Also inhibits PDGFR-β, c-Kit and c-Fms. Potent aromatase inhibitor (IC50 = 50 nM). Orally available.
Specifications
Specifications
Chemical Name or Material | N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate |
CAS | 212142-18-2 |
Synonym | CGP 79787D, PTK787/ZK222584 |
Quantity | 50 mg |
Target | VEGF Receptor Inhibitors |
Molecular Formula | C20H15ClN4.C4H6O4 |
Formula Weight | 464.9 |
Purity | >99% |
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