Invitrogen™ VCAN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119502

Catalog No. PIPA5119502

Description

VCAN Polyclonal Antibody for Western Blot, IHC (P)

Versican is a member of the family of large aggregating proteoglycans (also including aggrecan, brevican, and neurocan). The protein shows wide tissue distribution which includes fibrous, articular, and elastic cartilages, as well as nervous, epidermal, arterial, and loose connective tissues. Versican V1 has been shown to enhance cell proliferation, and also induce cell transformation and protect cells from apoptosis. This was demonstrated through its ability to downregulate the expression of proapoptotic Bad. Versican's existence as a extracellular matrix protein in human airways has also lead to the discovery of an inflammatory role in asthmatics.

Specifications

• Antigen: VCAN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VCAN
• Gene Alias: 5430420N07Rik; 9430051N09; Chondroitin sulfate proteoglycan 2; chondroitin sulfate proteoglycan 2 (versican); chondroitin sulfate proteoglycan core protein 2; Cspg2; DPEAAE; ERVR; GHAP; glial hyaluronate-binding protein; hdf; heart defect; large fibroblast proteoglycan; NG2; PGM; PG-M; PG-M core protein; PG-M(V0); PG-M(V1); V1 Neo; VCAN; versican; versican core protein; Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M); versican proteoglycan; Versican V0; WGN; WGN 1; WGN1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1462
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P13611
• Gene Symbols: VCAN
• Immunogen: Recombinant protein Versican. The antigen corresponds to amino acid range 2958-3209 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG