VEGFR1/Flt-1 Antibody (FLT1/658), Alexa Fluor™ 700, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234618AF700

Catalog No. NBP234618Z

Description

VEGFR1/Flt-1 Monoclonal specifically detects VEGFR1/Flt-1 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: VEGFR1/Flt-1
• Classification: Monoclonal
• Conjugate: Alexa Fluor 700
• Gene Alias: EC 2.7.10, EC 2.7.10.1, FLT, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGFR1, VEGFR-1
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1 κ

• Applications: ELISA
• Clone: FLT1/658
• Dilution: ELISA
• Gene Symbols: FLT1
• Immunogen: Recombinant human VEGFR1/Flt-1 protein (Uniprot: P17948)
• Quantity: 0.1 mL
• Research Discipline: Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, HIF Target Genes, Hypoxia, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases
• Gene ID (Entrez): 2321
• Target Species: Human
• Form: Purified

For Research Use Only