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VEGFR1/Flt-1 Antibody (FLT1/658), DyLight 405, Novus Biologicals™
SDP

Catalog No. NBP234618V Shop All R&D Systems Products
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NBP234618V 0.1 mL
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Catalog No. NBP234618V Supplier Novus Biologicals Supplier No. NBP234618V
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Description

Mouse Monoclonal Antibody

VEGFR1/Flt-1 Monoclonal specifically detects VEGFR1/Flt-1 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen VEGFR1/Flt-1
Applications ELISA
Classification Monoclonal
Clone FLT1/658
Conjugate DyLight 405
Dilution ELISA
Gene Alias EC 2.7.10, EC 2.7.10.1, FLT, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGFR1, VEGFR-1
Gene Symbols FLT1
Host Species Mouse
Immunogen Recombinant human VEGFR1/Flt-1 protein (Uniprot: P17948)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, HIF Target Genes, Hypoxia, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases
Primary or Secondary Primary
Gene ID (Entrez) 2321
Test Specificity Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
Target Species Human
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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