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VEGFR2/KDR/Flk-1 Antibody (KDR657), Novus Biologicals™
SDP

Catalog No. NBP233000A Shop All R&D Systems Products
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NBP233000A 0.1 mg
NBP233000B 0.2 mg
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Catalog No. NBP233000A Supplier Novus Biologicals Supplier No. NBP2330000.1MG

Description

Mouse Monoclonal Antibody

VEGFR2/KDR/Flk-1 Monoclonal specifically detects VEGFR2/KDR/Flk-1 in Human samples. It is validated for Flow Cytometry.

Specifications

Antigen VEGF R2/KDR/Flk-1
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone KDR657
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1ug/million cells in 0.1ml, Immunofluorescence 0.5 - 1ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P35968
Gene Alias CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, FLK-1, FLK1tyrosine kinase growth factor receptor, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGFR, VEGFR2, VEGFR-2
Gene Symbols KDR
Host Species Mouse
Immunogen Recombinant human VEGF-R2 protein
Purification Method Protein A purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, HIF Target Genes, Hypoxia, Phospho Specific, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases
Primary or Secondary Primary
Gene ID (Entrez) 3791
Test Specificity CD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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