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VEGFR2/KDR/Flk-1 Antibody (KDR721), DyLight 550, Novus Biologicals™
SDP

Catalog No. NBP234658R Shop All R&D Systems Products
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Catalog No. NBP234658R Supplier Novus Biologicals Supplier No. NBP234658R
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Description

Mouse Monoclonal Antibody

VEGFR2/KDR/Flk-1 Monoclonal specifically detects VEGFR2/KDR/Flk-1 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen VEGFR2/KDR/Flk-1
Applications Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone KDR721
Conjugate DyLight 550
Dilution Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, FLK-1, FLK1tyrosine kinase growth factor receptor, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGFR, VEGFR2, VEGFR-2
Gene Symbols KDR
Host Species Mouse
Immunogen Recombinant human VEGFR2/KDR/Flk-1 protein (Uniprot: P35968)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, HIF Target Genes, Hypoxia, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases
Primary or Secondary Primary
Gene ID (Entrez) 3791
Test Specificity CD309, also known as VEGFR2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGFR2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Target Species Human
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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