Invitrogen™ VGF Monoclonal Antibody (9#)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA541690	Invitrogen™ MA541690	200 μL
PIMA543702	Invitrogen™ MA543702	20 μL

Description

VGF Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

VGF was initially identified as a rapidly regulated gene product in nerve growth factor-treated PC12 cells. This protein is synthesized in neurons in the central and peripheral nervous system as well as in the pituitary, adrenal medulla, endocrine cells of the stomach, and pancreatic beta cells. VGF is thought to be involved in organism energy balance and regulation of homeostasis as mice lacking this gene show deficits in these areas. More recent results suggest that VGF is upregulated by brain-derived neurotrophic factor (BDNF) and can stimulate the proliferation of hippocampal progenitor cells and produce antidepressant-like behavioral effects, suggesting that this pathway may be a suitable target for therapeutic treatments.

Specifications

• Antigen: VGF
• Concentration: 0.94 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: O15240
• Gene ID (Entrez): 7425
• Immunogen: Recombinant protein VGF Nerve Growth Factor Inducible. The antigen corresponds to amino acid range 330-449 of the target protein.
• Product Type: Antibody

• Clone: 9#
• Content And Storage: -20°C
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG2b κ
• Target Species: Human
• Gene: VGF
• Gene Alias: Antimicrobial peptide VGF[554-577]; Gm1052; NERP-1; NERP-2; Neuroendocrine regulatory peptide-1; Neuroendocrine regulatory peptide-2; neuro-endocrine specific protein VGF; Neurosecretory protein VGF; SCG7; SgVII; Vgf; VGF nerve growth factor inducible; VGF(180-194); VGF(24-63); VGF(375-407); VGF8a protein; VGF-derived peptide AQEE-30; VGF-derived peptide HFHH-10; VGF-derived peptide LQEQ-19; VGF-derived peptide TLQP-11; VGF-derived peptide TLQP-21; VGF-derived peptide TLQP-30; VGF-derived peptide TLQP-62
• Gene Symbols: VGF
• Primary or Secondary: Primary
• Purification Method: Protein A/G