Villin 1 Antibody (rVIL1/1325), Alexa Fluor™ 750, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP279943AF750

Catalog No. NB013099

Description

Villin 1 Monoclonal specifically detects Villin 1 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Villin 1
• Classification: Monoclonal
• Conjugate: Alexa Fluor 750
• Formulation: 50mM Sodium Borate
• Gene Symbols: VIL1
• Immunogen: A recombinant fragment (around aa179-311) of human Villin 1 protein (exact sequence is proprietary) (Uniprot: P09327)
• Quantity: 0.1 mL
• Research Discipline: Cancer, Cell Biology, Cellular Markers
• Gene ID (Entrez): 7429
• Target Species: Human
• Form: Purified

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
• Clone: rVIL1/1325
• Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
• Gene Alias: D2S1471, VIL, villin 1, villin-1
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 95kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG1 κ