VNN1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-3575	Proteintech Group Inc 217451AP150UL	150 μL

Description

Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes. GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells. Vanin-1 is ubiquitously expressed as a pantetheinase enzyme and catalyzes the hydrolysis of pantetheine for vitamin B5 recycling. The hydrolytic activity of vanin-1 generates the potent antioxidant cysteamine as a metabolite. As a membrane bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions. In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, where it aids in cell migration.

Specifications

• Antigen: VNN1
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: O95497, Q9Z0K8
• Gene ID (Entrez): 22361, 8876
• Immunogen: VNN1 Fusion Protein Ag16501
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: VNN1

• Concentration: 0.37 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: HDLCQ8, Pantetheinase, Pantetheine hydrolase, Tiff66, vanin 1, VNN1
• Gene Symbols: VNN1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody