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Von Willebrand Factor Antibody (F8/86), DyLight 594, Novus Biologicals™
SDP

Catalog No. NB008116 Shop All R&D Systems Products
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NB008116 0.1 mL
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Catalog No. NB008116 Supplier Novus Biologicals Supplier No. NBP254379DL594
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Description

Mouse Monoclonal Antibody

Von Willebrand Factor Monoclonal specifically detects Von Willebrand Factor in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Von Willebrand Factor
Applications Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone F8/86
Conjugate DyLight 594
Dilution Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
Gene Symbols VWF
Host Species Mouse
Immunogen Von Willebrand Factor isolated from human plasma (Uniprot: P04275)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer
Primary or Secondary Primary
Test Specificity von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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