Von Willebrand Factor Antibody (VWF/1465), DyLight 594, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP254430DL594

Catalog No. NB008215

Description

Von Willebrand Factor Monoclonal specifically detects Von Willebrand Factor in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Von Willebrand Factor
• Classification: Monoclonal
• Conjugate: DyLight 594
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: VWF
• Immunogen: Recombinant fragment of human Von Willebrand Factor protein (aa1815-1939) (exact sequence is proprietary) (Uniprot: P04275)
• Quantity: 0.1 mL
• Research Discipline: Cancer
• Test Specificity: von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: VWF/1465
• Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
• Gene Alias: coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG1 κ